What is chiral inositol?
Chiral inositol is a naturally occurring stereoisomer of inositol, belonging to compounds related to the B vitamin group, and participates in various metabolic processes in the human body. Its chemical structure is similar to that of other inositols (such as myo-inositol), but the spatial configuration is different, which leads to differences in its physiological functions.
What foods are the sources of chiral inositol?
Whole grains (such as oats, brown rice), beans (black beans, chickpeas), nuts (walnuts, almonds).
Some fruits (such as Hami melons and grapes) and vegetables (such as spinach and broccoli) also contain small amounts.
What is the main function of chiral inositol?
1: Improve insulin resistance
● Mechanism: Chiral inositol can enhance insulin signaling, promote the uptake and utilization of glucose by cells, and thereby reduce blood sugar levels
● It is applicable to insulin resistance-related diseases, such as type 2 diabetes and polycystic ovary syndrome (PCOS). Studies have shown that patients with PCOS often have chiral inositol deficiency, and supplementation can improve symptoms such as irregular menstruation and hyperandrogenemia.
● It can assist in regulating glucose metabolism and may reduce the dependence of diabetic patients on hypoglycemic drugs.
2: Regulate hormone balance
● Reduce serum testosterone levels and improve hyperandrogenic symptoms such as hirsutism and acne in patients with PCOS.
Promoting follicular development and increasing ovulation rate may improve fertility.
3: Antioxidant and anti-inflammatory
● Chiral inositol has the ability to eliminate free radicals, can alleviate oxidative stress damage, inhibit chronic inflammatory responses, and may have preventive effects on cardiovascular diseases, non-alcoholic fatty liver disease, etc
Other potential functions
● Regulating blood lipids: It may reduce the levels of low-density lipoprotein (LDL-C) and triglycerides, and increase the levels of high-density lipoprotein (HDL-C).
Neuroprotection: It participates in signal transduction in the nervous system and may have a certain preventive effect on neurodegenerative diseases such as Alzheimer’s disease.
4:The differences from other inositols
| Types | Chiral inositol (DCI) | Myo-inositol (MI) |
| construction | Single stereoisomer | The most common form of natural inositol |
| insulin resistance | significantly improve | Auxiliary improvement needs to be coordinated with DCI |
| PCOS Application | regulatory hormone | It is used in combination with DCI in a ratio of 40:1 |
| source of food | low in content | It is widely present in food |
The research on chiral inositol is advancing from “metabolic regulation” to “precise intervention”. With the innovation of preparation techniques and the in-depth analysis of molecular mechanisms, DCI is expected to play a greater role in fields such as diabetes, PCOS, and neurodegenerative diseases. However, its application still needs to strictly follow the individualized principle and avoid blind supplementation. In the future, with the implementation of large-scale clinical trials, DCI may become a “new star” in the field of metabolic health.
Contact:Judy Guo
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Post time: Aug-06-2025