Iyini i-Urolithin A? Hlola izinzuzo zayo kanye nezicelo

Ukuqonda i-Urolithin A

I-Urolithin A iyi-metabolite ekhiqizwa i-gut microbiota evela e-ellagitannins, etholakala ezithelweni ezihlukahlukene, ikakhulukazi amahalananda, amajikijolo namantongomane. Le nhlanganisela idonse ukunaka okukhulu ngezinzuzo zayo zezempilo ezingaba khona, ikakhulukazi ezindaweni zempilo yamaselula, ukulwa nokuguga, kanye nokusebenza kwe-metabolic.

Ucwaningo lwakamuva lubonise ukuthi ukuthatha i-1 gram ye-Urolithin A nsuku zonke amasonto ayisishiyagalombili kungathuthukisa kakhulu amandla okuzithandela nokuqina kwemisipha yokuzithandela. Lokhu kuthola kugqamisa amandla ayo njengesengezo esinamandla kulabo abafuna ukuthuthukisa ukusebenza komzimba kanye nempilo yonke.

Imiphumela ye-Urolithin A Ekulaleni

Esinye sezici ezikhanga kakhulu ze-Urolithin A yikhono layo lokuthuthukisa ikhwalithi yokulala. Ucwaningo luye lwabonisa ukuthi i-Urolithin A ingalawula isigqi seselula ngezilinganiso eziningi, okubalulekile ekugcineni umjikelezo wokulala onempilo. Emhlabeni wethu wesimanje osheshayo, abantu abaningi babhekana “ne-social jet lag” ngenxa yamahora okusebenza angajwayelekile, umsebenzi wamashifu, nokuhamba njalo ezindaweni zesikhathi. I-Urolithin A ibonisa isithembiso ekwehliseni le miphumela, isiza abantu bathole ukuphumula, ukulala okubuyisela.

Ngokuthuthukisa ikhwalithi yokulala, i-Urolithin A ayisizi nje ukuthuthukisa impilo yomzimba, kodwa futhi ikhuthaza impilo yengqondo. Ukulala kwekhwalithi kubalulekile ekusebenzeni kwengqondo, ukulawula imizwa, nokwaneliseka kwempilo iyonke. Ngakho-ke, ukufaka i-Urolithin A ekuphileni kwansuku zonke kungase kuguqule impilo yalabo abahlushwa izinkinga ezihlobene nokulala.

Ukuqhathanisa nokusebenzisa i-NMN ne-NR

Nakuba i-Urolithin A yenze amagagasi embonini yokwengeza, kuyadingeka ukuyiqhathanisa nezinye izinhlanganisela ezaziwa njenge-NMN ne-NR. Kokubili i-NMN ne-NR zingamanduleli we-NAD+ (nicotinamide adenine dinucleotide), i-coenzyme ebalulekile ehilelekile kumetabolism yamandla kanye nokulungisa amaseli.

I-NMN (Nicotinamide Mononucleotide): I-NMN idume ngamandla ayo okwandisa amazinga e-NAD+, angase athuthukise ukukhiqizwa kwamandla, athuthukise impilo ye-metabolic, futhi akhuthaze ukuphila isikhathi eside. Ivamise ukukhangiswa njengesengezo sokulwa nokuguga.

- I-NR (Nicotinamide Riboside): Ngokufanayo ne-NMN, i-NR ingenye isandulela se-NAD+ esifundelwe izinzuzo zayo ezingaba khona kumetabolism yamandla kanye nezindaba zezempilo ezihlobene nobudala.

Nakuba kokubili i-NMN ne-NR igxile ekwandiseni amazinga e-NAD+, i-Urolithin A inikeza indlela eyingqayizivele ngokuthuthukisa ukusebenza kwe-mitochondrial nokuthuthukisa impilo yemisipha. Lokhu kwenza i-Urolithin A ibe umphelelisi omkhulu we-NMN ne-NR enikeza indlela ephelele yezempilo nokuphila kahle.

Ikusasa le-urolithin A

Njengoba ucwaningo luqhubeka nokujula, amathemba e-Urolithin A ayakhanya. Ikhono layo lokuthuthukisa ikhwalithi yokulala, ukuqinisa amandla, kanye nokusekela inhlalakahle jikelele kuyenza ibe isengezo esihle emakethe yezithasiselo.

Inkampani yethu ihamba phambili kule ntuthuko ethokozisayo, ihlinzeka nge-Urolithin A yekhwalithi ephezulu nezinye izinto zokusetshenziswa ezintsha ezisekelwa ucwaningo lwesayensi. Siyaziqhenya ngokuba ne-R&D eqinile nethimba lokuhlola ikhwalithi ukuze siqinisekise ukuthi imikhiqizo yethu ihlangabezana nezindinganiso eziphakeme kakhulu. Ithimba lethu eliphelele lokuthola usizo lisebenza kanzima ukuze lithole izinto zokusetshenziswa ezinhle kakhulu, liqinisekisa ukuthi amakhasimende ethu athola kuphela imikhiqizo ehamba phambili.

Singathola i-Urolithin A ekudleni?

Inemisebenzi enamandla ngokwedlulele njengemiphumela yokulwa nokuguga, amandla aqinile e-antioxidant, amandla okubuyisela ukusebenza kwamaseli aguga e-hematopoietic stem, ukuthuthukisa ukuzivikela komzimba kanye nokuzwela kwe-insulin, ukubuyisela emuva ukulimala kwesibindi noma izinso, ukunciphisa ukuguga kwesikhumba, nokuvimbela nokwelapha isifo i-Alzheimer's. Singakuthola ekudleni kwemvelo?

I-Urolithin A iyi-metabolite ekhiqizwa yi-microbiota yamathumbu evela e-ellagitannins (ETs) ne-ellagic acid (EA). Kuyathakazelisa ukuthi amaphesenti angama-40 kuphela abantu abangayiguqula ngokwemvelo besuka ezithakweni ezithile ekudleni kwabo kwansuku zonke. Ngenhlanhla, izithasiselo zingawunqoba lo mkhawulo.